There was carried out the method of HPLC-analysis of them on the chromatograph «Milichrom-5» (Russia) in the isocratic regime (stationary phase – «Diasorb C18», mobile phase - mixture of acetonitrile and water in relationship 75:25, flow rate – 0,1 ml/min) with the detection of lignans by means of the analytical wavelength at λmax 254 and 280 nm. It was established, that the content of two dominating lignans in fruits is varied from 1,17 % to 1,27 %, in seeds – from 2,74 % to 2,86 %, in the tincture of fruits – from 0,37 % to 0,39 %, in the tincture of seeds – from 0,34 to 0,91 % (calculated on γ-schizandrin). The relative degrees of the determination of the content of two dominating lignans in developed methodics with confidence probability 0,95 are no more than ±2,20 % (in the fruits of Schizandra chinensis), ±1,53 % (in the seeds of Schizandra chinensis), ±4,55 % (in the tincture of Schizandra chinensis fruits and ±4,35 % (in the tincture of Schizandra chinensis seeds).